Inspired Nutra - DVST8 Global
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3D Pump Breakthrough (6000mg)
3DPUMP Breakthrough is a blend containing L-citrulline, glycerol and amla fruit extract. A full dose of two scoops provides 3 grams of vegan fermented L-citrulline, 1.2 grams of glycerol, and 200 milligrams of amla fruit extract.
A placebo-controlled pilot study included in the patent showed significant benefits of the blend over its individual ingredients when tested in weight-trained men in their late 20s, particularly when glycerol was combined with Amla; this resulted in larger increases in thigh circumference and total body mass.
The role of amla fruit extract (scientifically known as Phyllanthus emblica or Indian gooseberry) in cardiovascular health due to its antioxidant properties and potential to improve blood flow is generating interest for its use in pre-workout supplements.
L-Citrulline is known to increase nitric oxide levels, which promotes vasodilation, improves blood flow, and allows for better nutrient delivery to muscles. It is preferred over L-arginine due to its slower metabolism, which helps to effectively increase nitric oxide levels in the body. This amino acid is associated with several benefits including increased endurance and recovery, primarily due to improved ATP production.
Known as "hyperhydration" by increasing water retention in the body, glycerol can improve endurance and thermoregulation when combined with adequate water intake. It also plays a crucial role in cell volumization, a desirable effect for athletes.
Betaine Nitrates (NO3-T) (2000mg)
Betaine Nitrate (NO3-T) has been included as an excellent source of nitrates. Nitrates occur naturally in various plants and vegetables and follow a specific pathway in the body, converting into nitrites and then into nitric oxide through a series of reactions involving various organs. This nitrate-nitrite pathway works independently but in parallel to the nitric oxide synthase (NOS) pathway and produces similar positive results such as improved blood flow, increased athletic performance and better endurance.
PeakO2 (1000mg)
PeakO2 is an adaptogenic blend of six different mushroom species, including Cordyceps militaris as the main ingredient, as well as others such as Reishi and Lion's Mane. These adaptogens help increase physical and mental performance by helping people adapt to various stresses and improving endurance and strength levels.
Research studies have validated the effectiveness of PeakO2 in improving work capacity through better oxygen utilization and reducing lactate buildup in the body. A 2015 study from the University of North Carolina found that taking 1.3 g of PeakO2 three times daily for three weeks significantly improved time to exhaustion, performance and VO2 Max in participants compared to a control group. PeakO2 not only serves as a beneficial component for overall health and immunity, but also as a boon for athletes who want to increase their endurance.
Betaine Anhydrous (Trimethylglycine) (1000mg)
Betaine Anhydrous is known to promote the transfer and retention of water in cells and, in synergy with glycerol in 3D PUMP, to increase cell volumization. Studies suggest that varying doses of betaine can provide multiple athletic benefits, including improvements in endurance and strength as well as increased muscle pumps with adequate water intake.
Research conducted in the late 2010s showed that a daily intake of 2.5 grams of betaine can promote muscle growth and increase arm size in trained individuals. This daily dose was also shown to promote muscle protein synthesis, similar to the functions of creatine, and was found to be beneficial in improving performance and reducing fat in women.
L-Tyrosine (1000mg)
L-Tyrosine is a popular addition in pre-workout supplements due to its role as a precursor to several "feel-good" neurotransmitters, including norepinephrine and dopamine, which can increase alertness and concentration while reducing anxiety and stress. In a pre-workout context, it can stimulate the sympathetic nervous system and enhance the "fight" response in "fight or flight" mode, which is beneficial during exercise.
Additionally, research from the US military has highlighted the effectiveness of L-Tyrosine in supporting sleep-deprived individuals, improving their performance, particularly when used in conjunction with caffeine.
Betaine Nitrates (NO3-T) (2000mg)
Betaine Nitrate (NO3-T) has been included as an excellent source of nitrates. Nitrates occur naturally in various plants and vegetables and follow a specific pathway in the body, converting into nitrites and then into nitric oxide through a series of reactions involving various organs. This nitrate-nitrite pathway works independently but in parallel to the nitric oxide synthase (NOS) pathway and produces similar positive results such as improved blood flow, increased athletic performance and better endurance.
CoLEAN (1000mg)
CoLEAN provides 400 milligrams of total choline, derived from a combination of Alpha-GPC, Choline DL-Bitartrate and Citicoline. This blend is preferred to promote cognitive improvement and enhance the "mind-muscle connection" during exercise compared to some individual cholinergic supplements.
Choline, essential for healthy organ function and cellular structure, is used in pre-workout supplements primarily as a precursor to the neurotransmitter acetylcholine, also known as the "learning neurotransmitter." Acetylcholine plays a crucial role in signaling muscle contractions and supports balance, coordination, memory and general learning, improving the exercise experience. The CoLEAN blend is characterized by different bioavailability profiles, mechanisms and absorption rates due to the unique properties of its individual components:
Alpha-GPC is valued for its ability to cross the blood-brain barrier and facilitate the synthesis of acetylcholine, which has contributed to its increasing popularity.
Choline DL bitartrate is characterized by its bioactive L form, which is more effective in the human body.
Citicoline can potentially increase norepinephrine and dopamine levels while increasing the density of dopamine receptors, creating a positive feedback mechanism during its use.
Caffeine Anhydrous (325mg)
DVST8 Global contains an impressive 325 milligrams of caffeine. Research shows that caffeine improves performance by crossing the blood-brain barrier to inhibit adenosine and phosphodiesterase, reducing fatigue and slightly increasing fat burning, providing more energy during exercise. Caffeine is also associated with increased strength and performance.
SYNapsis (132mg)
Citrus Aurantium, standardized to 30% alkaloids, provides a significant but not overwhelming dose of the popular fat burner synephrine.
Synephrine targets the beta-3 adrenergic receptors in adipose tissue by increasing the body's ability to oxidize fat through cAMP activation without causing a significant increase in blood pressure or heart rate. A 2016 double-blind, placebo-controlled study in 18 healthy participants suggested that synephrine could significantly increase fat burning rates during exercise compared to a placebo. It works well in conjunction with caffeine by promoting fat burning during exercise.
Methylliberin (125mg)
Methylliberin, also known by the brand name Dynamine, is used as a "neuroactivation" ingredient in DVST8 Global. It is contained at 40% strength, which is equivalent to 50 milligrams of active methylliberin. This amount is said to increase cognitive well-being and potentially improve mental energy, performance and concentration, especially when used synergistically with caffeine.
Methylliberin has been shown to increase energy in a manner similar to caffeine without affecting the cardiovascular system in the same way. It works by increasing the production of neurotransmitters such as dopamine and norepinephrine while inhibiting adenosine.
Theobromine (50mg)
Theobromine is similar to caffeine in its effects on the brain and helps inhibit phosphodiesterase and adenosine. However, it has a longer half-life, resulting in sustained energy. Its inclusion in the supplement aims to enhance the experience by rounding out the energetic effects of caffeine and Dynamine to create a longer energy profile and potentially improve the "feel" compared to pure caffeine, based on results of a study .
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